Early graft dysfunction and mortality rate in marginal donor liver transplantation

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Early graft dysfunction and mortality rate in marginal donor liver transplantation.

BACKGROUND/AIM To determine the effect of marginal donor livers on mortality and graft survival in liver transplantation (LT) recipients. MATERIALS AND METHODS Donors with any 1 of following were considered marginal donors: age ≥65 years, sodium level ≥ 165 mmol/L and cold ischemia time ≥ 12 h. Donors were classified according to the donor risk index (DRI) < 1.7 and ≥ 1.7. The transplant reci...

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Marginal grafts increase early mortality in liver transplantation.

CONTEXT AND OBJECTIVE Expanded donor criteria (marginal) grafts are an important solution for organ shortage. Nevertheless, they raise an ethical dilemma because they may increase the risk of transplant failure. This study compares the outcomes from marginal and non-marginal graft transplantation in 103 cases of liver transplantation due to chronic hepatic failure. DESIGN AND SETTING One hund...

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Small graft for living donor liver transplantation.

OBJECTIVE To evaluate the impact of graft size on recipients in living donor liver transplantation (LDLT) to establish a clinical guideline for the minimum requirement. SUMMARY BACKGROUND DATA Although the minimum graft size required for LDLT has been reported to be 30% to 40% of graft volume (GV)/standard liver volume (SLV), the safety limit of the graft size was unknown. METHODS A total o...

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Post-reperfusion Liver Biopsy and Its Value in Predicting Mortality and Graft Dysfunction after Liver Transplantation

Background: The outcome of the patients after liver transplant is complex and to characterize the risk for complications is not always easy. In this context, the hepatic post-reperfusion biopsy is capable of portraying alterations of prognostic importance. Aim: To compare the results of liver transplantation, correlating the different histologic features of the hepatic post-reperfusion biops...

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Graft calcifications and dysfunction following liver transplantation

BACKGROUND The molecular events, following ischemia and reperfusion (I/R) of the liver during transplantation are largely unknown. There is evidence that apoptotic and necrotic events may take place, and occasionally result in primary graft dysfunction. We herein report two cases, where significant I/R injury correlated with the development of liver calcification and primary liver dysfunction. ...

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ژورنال

عنوان ژورنال: TURKISH JOURNAL OF MEDICAL SCIENCES

سال: 2014

ISSN: 1300-0144,1303-6165

DOI: 10.3906/sag-1306-123